Nai Duniya, Health, Raipur May 2008. Psoriasis
Psoriasis is an immune-mediated disease that affects the skin. It is
typically a lifelong condition. There is currently no cure, but various
treatments can help to control the symptoms.
Some patients, though, have no
dermatological signs or symptoms. The name psoriasis (????as??) is from
the Greek language, meaning roughly "itching condition" (psora "itch" +
-sis "action, condition") and knees, but can affect any area, including
the scalp, palms of hands and soles of feet, and genitals. In contrast to
eczema, psoriasis is more likely to be found on the outer side of the
The disorder is a chronic recurring condition that varies in severity from minor localized patches to complete body coverage. Fingernails and toenails are frequently affected (psoriatic nail dystrophy) and can be seen as an isolated sign. Psoriasis can also cause inflammation of the joints, which is known as psoriatic arthritis. Between 10% and 30% of all people with psoriasis also have psoriatic arthritis.
The cause of psoriasis is not fully understood, but it is believed to have a genetic component and local psoriatic changes can be triggered by an injury to the skin known as the Koebner phenomenon.Various environmental factors have been suggested as aggravating to psoriasis, including oxidative stress, stress, withdrawal of systemic corticosteroid, as well as other environmental factors, but few have shown statistical significance. There are many treatments available, but because of its chronic recurrent nature, psoriasis is a challenge to treat. Withdrawal of corticosteroids (topical steroid cream) can aggravate the condition due to the 'rebound effect' of corticosteroids.
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